江汉大学学报（自然科学版）

目的:研究镇静催眠药急性中毒患者的流行病学特点,探讨其预防和治疗对策。方法:采用回顾性研究方法,对2001年1月至2010年12月武汉市第五医院消化内科收治的132例镇静催眠药急性中毒患者的一般情况、诊疗经过、预后等项目进行统计分析。结果:中毒患者男女比例为1∶5;中毒年龄主要集中于20～39岁;就诊时间分布无规律性,12月～2月相对高发;所有患者均为自杀;服毒药物以安定、舒乐安定为主;经相应治疗127例治愈出院,死亡2例。结论:132例患者中,文化程度偏低的女性待业或务农青年居多,病情多为中、重度,经过适当、及时的治疗,多数患者仍能抢救成功。

Objective:To explore the epidemiological characteristics of acute poisoning patients with sedatives and hypnotics.Methods:132 cases of acute poisoning with sedatives and hypnotics from January 2001 to December 2010 were reviewed retrospectively including general conditions,process of diagnosis and treatment,prognosis.Results:The poisoning proportion of male:famale was 1∶5,the main poisoning age was 20-39 years old.Visiting time distribution was irregular.The peak time of poisoning was from December to February and all of the patients were suicide.Diaza pam and estazolam were the main poisoning drugs.After corresponding treatment,127 cases were healed.Fatalities were reported for only 2 cases.Conclusion:Unemployed women with low educa tional level or farming young people were the main poisoning patients in 132 cases,more condi tions were moderate or severe,with appropriate and timely treatment,most patients can be success ful rescued.