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目的 :探讨普伐他汀治疗老年人高脂血症的临床效应和安全性。方法 :将 43例老年高脂血症患者随机分为两组 :普拉固组和多烯康组 ,治疗 8周后观察血脂变化和安全性 ,并加以比较。结果 :普拉固组能显著降低老年人的血清 TC、L DL -C、apo- B,升高 HDL- C、apo A1 、apo A1 / apo B,明显优于多烯康组。结论 :普伐他汀具有显著的降脂作用和调脂功能 ;安全性方面 ,未发现有临床意义的毒副作用
Abstract:Objective: To study clinical efficary and safety of pravastatin on olderly hypercholesterolemia. Methods: Forty-three olderly hypercholesterolmia patients were divided into pravastatin group (n=28) and doxicang group (n=25), The lipid and safety was study after eight weeks. Results: There were lower levels of oderly TC、 LDC-C、 apoB and higher HDL-C、 apoA 1/apoB, all in pravastatin group than doxicang group. Conclusion: Pravastatin is good effective and safe in the treating olderly hypercholesterolemia.
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基本信息:
DOI:
中图分类号:R589.2
引用信息:
[1]张刚成,钟耀生.小剂量普伐他汀治疗中国老年人高脂血症的效应和安全性[J].武汉市职工医学院学报,2000(03):11-12+40.
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