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2002, 03, 29-30
老年高血压患者血清瘦素水平的临床研究
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发布时间: 2002-09-30
出版时间: 2002-09-30
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摘要:

目的 :探讨老年高血压患者血清瘦素 (Leptin)水平变化及意义。方法 :采用放射免疫测定 41例老年高血压患者和 2 5例老年非高血压患者血清瘦素与正常人对照。结果 :老年高血压组血清瘦素明显高于正常对照组 (P <0 .0 1) ,也高于老年非高血压组 (P <0 .0 5 )。结论 :老年高血压患者血清瘦素较非高血压者高 ,提示血清瘦素与高血压有显著的相关性

Abstract:

Objective: To investigate the variation and significance of serum leptin in the hypertensive.Methods: 41 cases of the elderly hypertensive were determined for the serum leptin with radio immunoassay. The result was compared with that of 25 cases of the elderly non hypertensive and normal controls.Results: The serum leptin level of the elderly hypertensive is obviously higher than that of normal controls ( P < 0.01 ) and also is higher than that of the elderly non hypertensives ( P < 0.05 ). Conclusion: The serum leptin levels of the elderly hypertensive is higher than that of non hypertensives. It suggests that serum leptin is highly correlated with hypertention.

参考文献

[1] WangHuo wei,ZhouYan ting,TetsuyaKakuma,etal.UngerComparingthehypothalamicandextrahypotha lamicactionsofendgenoushyperleptinemia[J].ProcNatlAcadSci,1999,96:10373.

[2] 吴木潮综述,钟光恕审校.瘦素与代谢综合征[J].国外医学内科学分册,2000,12:519.

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[4] SanchezRodrlguezM ,GarciaSanchezA ,Retana ugaldeR ,etal.Serumleplinlevelsandbloodpressureintheoverweightelderly[J].ArchMedRes,2000JulAug,31(4):425.

[5] 顾已琼,陈名道,唐金凤,等,中国人血清瘦素水平与肥胖的关系[J].中华内分泌杂志,1999,15(1):15.

[6] MallamaciF ,CuzzolaF ,TripepiG ,etal.Gender de pendentdifferencesinplasmaleptininessentialhyper tension[J].AmJHypertens.2000Aug,13(8):914.

[7] SheuWH ,LeeWJ ,ChenYT .HighplasmaleptinCon centrationsinHypertensivemenbutnotinhypertensiveWomen[J].JHypertens,1999Sep,17(9):1289.

基本信息:

中图分类号:R544.1

引用信息:

[1]徐慧勤,郭秋慧,吴绍清,钟淙,毕军华,李红,许立天.老年高血压患者血清瘦素水平的临床研究[J].江汉大学学报(医学版),2002(03):29-30.

发布时间:

2002-09-30

出版时间:

2002-09-30

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