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目的:分析武汉地区原发性肝癌患者HBV感染情况及基因型分析。方法:利用HBV检测引物及分型引物对肝癌患者血清进行PCR,通过电泳检测PCR特异性产物。结果:50例患者血清中44例HBV DNA呈阳性,占总数的88%;其中30例为C型占68%,14例为B型占32%。结论:武汉地区原发性肝癌患者多为HBV感染患者,而且以HBV C型感染为主。
Abstract：Objective: HBV infection state of primary hepatocellular carcinoma and HBV genotypes were investigated.Methods: The HCC patient serum was determined by special primer with PCR.Results: The positive rate of HBV was 88% in HCC(44/50) and HBV C genotype was 68%(30/44),HBV B genotype was 32%(14/44).Conclusion: Primary hepatocellular carcinoma in Wuhan area is mostly the HBV infection patients,and most of them are HBV C-type infection patients.
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基本信息:
中图分类号:R735.7
引用信息:
[1]韩雪,黄晶,杨卫萍.武汉地区肝癌患者中HBV基因型分析[J].江汉大学学报(自然科学版),2012,40(02):74-76.
基金信息:
湖北省自然科学基金项目(2008CDB057)
2012-04-12
2012-04-12